LifeLine™ - Highlights

This software uses probabilistic techniques to model exposure, risks and benefits for the general population or for selected subpopulations such as children, women of childbearing age or the elderly.

Sources of Exposure Included in the Model
  • Diet
  • Home Environments and Products
  • Drinking and Tap Water
  • Consumer Products
  • Pesticide Users
OR an AGGREGATE of all these sources

Routes of Exposure Considered in the Model
  • Inhalation
  • Dermal Penetration
  • Oral from Diet, Child's Mouthing Behaviors
Estimates of exposure via these routes are linked to physiological dynamics and toxicology

LifeLine™ Version 5 provides a modification to LifeLine™ Version 4.3 that allows the analyst to complete both the model run and a summary report within the same process. The analyst may now choose to generate a summary report as required for submissions to US Environmental Protection Agency's Office of Pesticide Programs at the point of setting the parameters of the analysis. This will increase the efficiency of the modeling run.

LifeLine™ Version 5 is the most flexible dietary software available for pesticide and chemical exposure and risk assessments. Residue files created with DEEM™ software can be imported and dietary exposure estimates produced. This eliminates the need to re-enter data or purchase expensive new software.

EPA imported DEEM™ files into the LifeLine software and performed the dietary portion assessment for cumulative risks of organophosphorous pesticides.

EPA is currently using Version 5 to assess dietary, aggregate and cumulative risks of pesticides.

Previous versions of LifeLine™ software have been reviewed by EPA's Science Advisory Panel who concluded:

"The developers are to be congratulated for their efforts with the LifeLine™ software. Modeling microexposure events is needed to estimate cumulative and aggregate exposures accurately, and the tool they have created should be very useful for these comprehensive exposure assessments."

Science Advisory Panel, March 2001